Our innovations

CELEOS crafts a unique solution that allows saving and contactless in situ sampling by laser, molecular analysis by mass spectrometry, and an explainable real-time AI framework for detailed tissue characterization and precise surgical margin definition.


What is different with SpiderMass ?


Our fibered laser offers a swift, precise and painless method to sample a microscopic volume of the tissue surface in the patient's body, without surrounding damages preserving integrity for the subsequent comprehensive pathological diagnosis.

Molecular characterisation

Mass spectrometry stands out for offering an unparalleled and deepest level of molecular details explaining why it holds such a prominent place in modern clinical diagnosis.
It explains why today's mass spectrometers are a far cry from the systems used in research laboratories just a few years ago, offering greater repeatability and reproducibility and requiring less maintenance.
Using MS, we have the capability to accurately measure the molecular characteristics of a tissue with great sensitivity, specificity and limit of detection. Our profiling technique simultaneously observe several hundreds of signals but also enables us to pinpoint specific molecules playing crucial role in the final tissue classification and clinical decision.

The biostatistical approach

We use cutting-edge machine learning techniques and innovative AI framework that enables real-time and interpretable tissue sorting.


applications :


SpiderMass holds promise for every solid cancer that benefits from surgical intervention. This includes tissue characterisation and margin delineation to enhance surgical precision. The capability to characterise other tissue states like inflammation and necrosis would also be greatly beneficial for clinicians.


Living in similar human environments, pets develop the same cancer than we do. SpiderMass can assist veterinarians in delivering high quality care to animals. Additionally, there are also interesting applications within the agronomy sector.

Dermatology & Cosmetology

The real-time non-destructive tissue characterisation and drug metabolism and pharmacokinetics (“DMPK”) offered by SpiderMass can significantly benefit the fields of skin diseases and cosmetics.

Other applications

Byond the mentioned areas, our technology has potential applications on-the-field making it possible to take out mass spectrometry analysis of the quality control laboratories for forensics, environmental analysis, and product quality control.


Read all our publications

7 July 2023

Ambient Mass Spectrometry Imaging by Water-Assisted Laser Desorption/Ionization for Ex Vivo and in Vivo Applications

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3 March 2022

Mass Spectrometry-Based Differentiation of Oral Tongue Squamous Cell Carcinoma and Nontumor Regions With the SpiderMass Technology

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12 November 2018

Real-Time Molecular Diagnosis of Tumors Using Water-Assisted Laser Desorption/Ionization Mass Spectrometry Technology

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Read all our patents

3 March 2023

Pending : Interface et procédé de préparation de matériel biologique pour son transfert dans un spectromètre de masse

3 March 2023

Pending : Interface et procédé de préparation de matériel pour son transfert dans un spectromètre de masse

22 September 2014

Device for real-time in vivo molecular analysis

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You saw 3 out of 3 patents

A question or a request?

Is there any application of the technology that interests you? You would like to learn more? Feel free to contact us!

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